Marcia Angell: “it is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as an editor of The New England Journal of Medicine[12].

12. Angell M. Drug companies and doctors: A story of corruption. January 15, 2009. The New York Review of Books 56. Available: Accessed 20 September 2010.